General Sarcoma

Nexavar Shows Promise against Drug-Resistant GIST (02-1-2011)

Among patients with gastrointestinal stromal tumors (GIST) that were resistant to both Gleevec® (imatinib) and Sutent® (sunitinib), treatment with Nexavar® (sorafenib) resulted in tumor shrinkage or stable disease in 68% of patients. The results of... Continue Reading

Kepivance Effective in Managing Mucositis in Patients Undergoing Multiple Cycles of Chemotherapy (10-5-2010)

A single dose of Kepivance® (palifermin) prior to each cycle of chemotherapy in sarcoma patients may substantially reduce the likelihood of moderate to severe mucositis. These findings from a randomized, double-blinded, placebo-controlled trial were... Continue Reading

High-risk Soft Tissue Sarcoma Patients Benefit from Targeted Heat Therapy Combined with Chemotherapy (05-7-2010)

A technique called regional hyperthermia (RHT) makes chemotherapy more effective and improves outcomes in patients with localized, high-risk soft tissue sarcoma, according to the results of a study recently published in the journal The Lancet.[1] These... Continue Reading

Targeted Heat Therapy Improves Outcomes for Soft Tissue Sarcoma (09-30-2009)

A new technique called regional hyperthermia (RHT) makes chemotherapy more effective and improves outcomes in patients with soft tissue sarcoma, according to the results of a study presented on September 22, 2009 at Europe’s largest cancer congress,... Continue Reading

Gleevec® Approved for Adjuvant Treatment of Gastrointestinal Stromal Tumors (03-8-2009)

Gleevec® Approved for Adjuvant Treatment of Gastrointestinal Stromal Tumors The U.S. Food and Drug Administration has expanded the approval of Gleevec® (imatinib mesylate) to include the adjuvant (post-surgery) treatment of Kit-positive gastrointestinal... Continue Reading

Differences in IMRT Radiation Doses May Complicate Study Results in Sarcomas (03-8-2009)

Differences in IMRT Radiation Doses May Complicate Study Results in Sarcomas Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison studies... Continue Reading

PET Scan More Accurate Predictor of Treatment Response for Soft Tissue Sarcomas (03-8-2009)

PET Scan More Accurate Predictor of Treatment Response for Soft Tissue Sarcomas Positron emission tomography (PET) scans were found to be significantly more accurate than standard methods in judging response to first-line treatment for high-grade soft... Continue Reading

Sutent® Linked with Heart Problems (03-8-2009)

Sutent® Linked with Heart Problems According to the results of a study published in the Lancet, treatment with Sutent® (sunitinib) was linked with the development of heart problems in some patients with metastatic gastrointestinal stromal tumors. Sutent... Continue Reading

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