Stages I-III Rectal Cancer

Addition of Eloxatin® Following Surgery Delays Cancer Progression in Certain Colorectal Cancers (07-28-2016)

The addition of the chemotherapy combination consisting of Eloxatin (oxalipatin) plus 5-fluorouracil (5 FU) following surgery reduces the risk of cancer progression among patients with deficient mismatch repair (dMMR) stage III colorectal cancer. These... Continue Reading

Vectibix® Improves Survival in Colorectal Cancer, Demonstrates Importance of Tissue Testing (01-28-2016)

The addition of Vectibix® (panitumumab) to best supportive care improves survival over best standard care alone among colorectal cancer patients who have stopped responding to chemotherapy. However, the benefit is only seen with patients who have no... Continue Reading

FOLFOX Improves Disease-Free Survival in Stage II and III Rectal Cancer Patients (06-11-2014)

Researchers at the University of Ulsan College of Medicine in South Korea reported that treatment with the FOLFOX chemotherapy regimen in rectal cancer patients improved 3-year disease-free survival over a standard chemotherapy of 5-FU/leucovorin. The... Continue Reading

Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (11-6-2012)

Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading

Adjuvant Therapy May Offer Survival Benefit in Older Patients with Colorectal Cancer (09-11-2012)

Adjuvant chemotherapy appears to offer a survival benefit to patients aged 75 years or older who have surgically resected colorectal cancer, according to the results of a study published in the Journal of Clinical Oncology. Colorectal cancer is the second... Continue Reading

Rectal Cancer Patients May Benefit from Higher Dose of Preoperative Radiation (10-12-2011)

Among rectal cancer patients treated with chemotherapy and radiation therapy prior to surgery, providing a higher dose of radiation therapy (50 Gy rather than 45 Gy) may reduce the risk of cancer recurrence. These results were presented at the 53rd Annual... Continue Reading

African Americans Most Willing to Exhaust Resources for Life-Extending Care (05-5-2011)

African Americans who are diagnosed with lung or colorectal cancer may be more willing than Whites to expend all personal financial resources in order to extend their lives. Other minority groups also appear more likely than Whites to use personal resources.... Continue Reading

Delay in Chemotherapy Increases Risk of Death in Colorectal Cancer (04-29-2011)

When chemotherapy for colorectal cancer is delayed by more than four weeks following surgery, patients face an increased risk of death. These findings were recently reported at the American Society of Clinical Oncology’s annual Gastrointestinal Cancers... Continue Reading

Pathological Complete Response Predicts Better Outcomes in Locally Advanced Rectal Cancer Patients (08-25-2010)

Among patients with locally advanced rectal cancer, a complete disappearance of detectable cancer (pathological complete response) after preoperative chemoradiation therapy is linked with better long-term outcomes. These findings were recently published... Continue Reading

Antibiotic Sponge Ineffective at Preventing Surgical Infection (08-12-2010)

Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England... Continue Reading

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