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BCR-ABL gene mutation analysis (12-7-2015)

Sometimes new changes (mutations) develop in the part of the BCR-ABL gene that makes the BCR-ABL protein. These mutations change the shape of the BCR-ABL protein, affecting how and which targeted cancer drugs can bind to it to block the growth signals.... Continue Reading

BCR-ABL (12-7-2015)

The exchange of genetic information that produces the Philadelphia chromosome brings together two genes: the BCR (breakpoint cluster region) gene on chromosome 22 and the ABL (Ableson leukemia virus) gene on chromosome 9.  The combination of these two... Continue Reading

Bone Marrow (12-7-2015) The soft, sponge-like tissue in the center of most bones where blood cells are made. ... Continue Reading

Blood stem cell (12-7-2015) An immature cell from which other types of blood cells develop. ... Continue Reading

Bursitis (10-6-2015) Inflammation of a bursa ... Continue Reading

Bursa (10-6-2015) A closed envelope-like sac lined with synovial membrane containing a thin layer of fluid. These are found in regions subject to friction, such as a bony prominence where a tendon passes over the bone ... Continue Reading

Bone morphogenetic protein (10-6-2015) A substance that is injected percutaneously into a bony structure and in particular into the vertebral body to stimulate bone formation and fracture repair ... Continue Reading

Blincyto® (05-19-2015)

Class: Biological Therapy Generic Name: blinatumomab Trade Name: Blincyto® For which conditions is this drug approved? Blincyto® is approved for treatment of a certain type of acute lymphoblastic leukemia (ALL): Philadelphia chromosome-negative relapsed... Continue Reading

blinatumomab (05-19-2015)

Class: Biological Therapy Generic Name: blinatumomab Trade Name: Blincyto® For which conditions is this drug approved? Blincyto® is approved for treatment of a certain type of acute lymphoblastic leukemia (ALL): Philadelphia chromosome-negative relapsed... Continue Reading

Beleodaq® (03-16-2015)

Class: Biological Therapy Generic Name: belinostat (be-LIN-oh-stat) Trade Name: Beleodaq® For which conditions is this drug approved? Beleodaq is approved for the treatment of peripheral T-cell lymphoma (PTCL) that comes back or does not respond to... Continue Reading

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