Graft-Versus-Host Disease (GVHD)

GVHD is a common side effect in people who receive cells from a donor (allogeneic transplant). It occurs when the transplanted cells recognize the recipient’s tissues as foreign and attack the tissues. This can cause a variety of problems, including skin rashes, liver problems, and diarrhea. There are two types of GVHD: acute GVHD, which often happens in the first three months after a transplant, and chronic GVHD, which can develop any time between three months and three years after the transplant. Both acute and chronic GVHD can be mild to serious. Medications and other treatments that suppress the immune system are used to prevent and treat GVHD until the donor cells stop attacking.